MingCeler tus thawj kws tshawb fawb

Dr. Guangming Wu, PhD

Dr. Guangming Wu, tus xibfwb ntawm Guangzhou Bio-land Laboratory, tau ua haujlwm ua tus kws tshawb fawb los yog tus kws kho mob tom qab kawm tiav ntawm New England Medical Animal Center, Brown University, University of Missouri-Columbia, Tuam Tsev Tsev Kawm Ntawv Tshuaj Kho Mob, thiab lwm lub koom haum tshawb fawb thoob ntiaj teb. .Xyoo 2004, nws tau koom nrog Max Planck lub koom haum rau Molecular Biology (MPI) hauv lub teb chaws Yelemees, qhov chaw nws tau ua haujlwm nrog Prof. Hans R. Schöler (Tus Tswv Cuab ntawm German National Academy of Sciences) ntawm kev txhim kho nas embryos thiab qia cell mechanisms.

Dr. Wu tau ua haujlwm ntawm cov txheej txheem molecular ntawm tib neeg, porcine, bovine, thiab nas oocyte thiab thaum ntxov embryonic txoj kev loj hlob, thiab kev tsim ntawm totipotency thiab pluripotency rau ntau tshaj 30 xyoo, thiab yog zoo versed nyob rau hauv ntau yam embryonic nyob rau hauv vitro kab lis kev cai thiab micro. manipulation cov txheej txheem.Nws yog thawj zaug thiab tam sim no tus kws tshawb fawb nkaus xwb txhawm rau nce tus nqi yug me nyuam ntawm tetraploid them nyiaj thev naus laus zis los ntawm 1-5% mus rau 30-60% los ntawm kev ua kom zoo, ua tiav kev lag luam ntawm cov thev naus laus zis.Nws tau koom ua ke 79 SCI cov ntaub ntawv nrog kev sib koom ua ke ntawm ntau dua 670 thiab tshaj 7150 cov ntawv sau tseg thiab tau luam tawm nyob rau hauv cov ntawv xov xwm thoob ntiaj teb xws li Nature, Cell stem cell, thiab lwm yam.

Rau nws txoj kev koom tes zoo rau kev tswj hwm lub embryo, Dr. Wu lub npe tau tso tawm mus tas li hauv Munich's Deutsches Tsev khaws puav pheej, uas yog lub ntiaj teb loj tshaj plaws kev tshawb fawb thiab thev naus laus zis tsev cia puav pheej.

Thaum Lub Yim Hli 2019, Dr. Wu tau qhia rov qab mus rau Tuam Tshoj ua tus kws tshawb fawb puv sijhawm, nws thiab nws pab pawg tshawb fawb tau ua tiav kev tsim tus qauv ACE2 humanized nas hauv 35 hnub, tso qhov kev sim "lub hauv paus" rau kev tshawb fawb ntawm COVID-19 pathogenesis, kev tshuaj xyuas tshuaj, thiab kev tsim tshuaj tiv thaiv.Vim nws qhov kev ua tau zoo tshaj plaws hauv kev tshawb fawb thiab thev naus laus zis, Dr. Wu tau txais txiaj ntsig "Tus Neeg Tshaj Lij Tshaj Lij Tshaj Lij Tshaj Lij Tshaj Lij Tshaj Lij Tshaj Lij Tiv Thaiv-19 hauv Guangdong Province" xyoo 2020.

Kev vam meej thiab kev siv cov thev naus laus zis thev naus laus zis thev naus laus zis tshaj plaws Tetraploid Complementation (TurboMice ™ thev naus laus zis) hauv kev ua qauv nas thaum sib ntaus sib tua tiv thaiv COVID-19, txhawb kom Dr. Wu siv zog kom muaj txiaj ntsig ntau dua hauv kev txhim kho biopharmaceuticals.Yog li ntawd, nws tau koom nrog Guangzhou MingCeler Biotech Co., Ltd ua tus kws tshawb fawb tseem ceeb, cog lus rau kev hloov pauv ntawm TurboMice ™ thev naus laus zis los ntawm chav kuaj mus rau kev lag luam siv los muab cov khoom lag luam siab kawg nas thiab cov kev pab cuam rau cov tsev kawm qib siab thoob ntiaj teb, cov koom haum tshawb fawb, tsev kho mob, thiab cov tuam txhab tshuaj koom nrog hauv kev tshawb fawb txog kev noj qab haus huv lub neej.